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In vitro intestinal permeability assay Permeability assay with fluorescein isothiocyanate (FITC)-Dextran 4 kDa (Sigma) in the 2D intestinal models were performed on day eight

In atherosclerotic lesions, monocytes, macrophages, endothelial cells, vascular smooth muscle cells, and platelets all show iron overload, and their involvement promotes the progression of atherosclerosis (Vinchi et al., 2014)

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Dietary fiber-derived SCFAs suppress intestinal inflammation by inhibiting the activation of the NLRP3 (NLR family pyrin domain containing 3) inflammasomea multiprotein complex that mediates caspase-1-dependent maturation of IL-1

That adds up quickly across a 24 to 48 week research period

Other functions in cellular metabolism In addition to its importance for energy production, L-carnitine was shown to display direct antioxidant properties in vitro (15)