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But that peripheral-only action means it does not suppress appetite, does not change energy expenditure through central pathways, and does not produce the dramatic caloric deficits that GLP-1 agonists like semaglutide or tirzepatide create

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Cluster analyses could help identify patients with high emotional dysregulation, identity-related challenges, or entrenched maladaptive coping strategies who might need a stabilizing phase of psychotherapy before starting pharmacotherapy

The liver plays a central role in nutrient distribution, glucose homeostasis, lipid regulation, and postprandial lipid flux

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