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6C, D), suggesting that, at least in the initial phase of treatment, these compounds drive their weight-lowering effects mostly by reducing food consumption, without inducing thermogenic responses

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GNC also ran a study of participants on GLP-1s and found they were not meeting their dietary reference intakes, as calorie and protein consumption appeared suboptimal when they were on the weight loss medications

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Next, we evaluated the NRF2-mediated cardio-protective pathways