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KauserHPalakeelJJAliMChaduvulaPChhabraSLamsal LamichhaneSet al

Cagrilintide, an amylin analogue, is advancing in combination with semaglutide in the Phase III CagriSema programme

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MC4R activation in hypothalamic nuclei modulates downstream dopaminergic and oxytocinergic neurotransmission pathways relevant to CNS arousal and energy balance research

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Compare this to short-acting GLP-1 agents with half-lives of hours, which require daily or twice-daily dosing