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A 2010 trial (N=412) demonstrated that tesamorelin reduced trunk fat by 15.2% over 26 weeks compared to 5.5% with placebo [5]

However, while p53 modulates SLC7A11 expression, the expression and activity of SLC7A11 and GPX4 are not associated with SAT1, and only ferrostatin-1 can inhibit ROS-induced ferroptosis in Tet-on cells (Ou et al., 2016)

Wang, L., Wang, N., Zhang, W., Cheng, X., Yan, Z., Shao, G., Wang, X., Wang, R., & Fu, C

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doi: 10.3390/jpm11111141