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Serious Side Effects to Monitor While uncommon, tirzepatide carries risks that require immediate attention: severe abdominal pain, persistent vomiting lasting more than a few hours, signs of pancreatitis (upper left pain, fever, rapid heartbeat), or allergic reactions (rash, difficulty breathing, swelling)

Magrone T, Russo MA, Jirillo E

Consumption of these products has resulted in numerous hospitalizations, [2] and the drugs have been reported to cause hallucinations, increased heartbeat and blood pressure, aggressive behavior, anxiety, muscle spasms, nausea, and vomiting

Some anecdotally report brief drowsiness

More specifically, alcohol consumption can result in: A drop-off in GABA activity, removing the initial calming effect provided by the alcohol 15

96 The major endogenous nonenzymatic low-molecular-mass antioxidants include N-acetylcysteine, glutathione, uric acid, melatonin, coenzyme Q and others