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Dry skin needs a strong hydration base before actives can do their best work

(Wikipedia) In senescent cells (cells that have permanently exited the cellcycle, accumulate damage, and secrete inflammatory factors), FOXO4 expression goes up and helps bind p53 in the nucleus, preventing p53 from driving those cells into apoptosis

Multifaced roles of the v3 integrin in ehlers-danlos and arterial tortuosity syndromes' dermal fibroblasts

Wound healing benefits become apparent relatively quickly in this timeframe