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[12] In July 2022, the Committee for Medicinal Products for Human Use of the European Medicines Agency adopted a positive opinion, recommending granting a marketing authorization for the medicinal product Mounjaro, intended for the treatment of type 2 diabetes

This GLP-R1 agonist seems to increase oncogenesis in multiple tissues, including the thyroid, bladder, pancreatic, and colorectal [97, 110, 121]

Per-protocol and as-treated analyses showed similar directions of association for anxiety and depression, although the strength of some associations varied depending on treatment persistence

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