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A meta-analysis of 45 randomized controlled trials observed a trend toward increased risk of thyroid dysfunction in patients treated with GLP-1 receptor agonists, although the findings did not reach statistical significance
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Ongoing guidance and support are provided while you are using the medication to ensure you get the best results with your safety as a priority
It also says anyone pregnant or breastfeeding, with liver disease, or taking immunosuppressants should discuss melatonin with a provider first, and notes melatonin may interact with blood thinners and diabetes medications
Encourage physical activity Combining GLP-1 therapy with physical activity supports outcomes beyond weight change
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