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Immunohistochemical staining in aged mice showed FOXO4 expression in Leydig cells, often with nuclear localization, whereas it was rarely expressed in young mice

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Acquired cryptorchidism is the condition in which one or both testicles cannot be returned into the scrotum after previously having been localized in a stable scrotal position (Table 1) [27]

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This switch is essential in inflamed synovium because it lowers inflammation markers such as IL-6 and tumor necrosis factor-alpha (TNF-) [87]

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