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The question in the title is worth taking apart before we answer it, because the phrase clinical research carries a specific weight

Chen X, Zhao X, Wang H, Yang Z, Li J, Suo H

Steroids, because they affect so many tissue types, generate a far wider and less predictable side effect profile

2 Methods A comprehensive literature search was performed using PubMed, Scopus, and Web of Science databases from their inception through June 2024

If you're on 10 mg vials and ramped too fast, the fix is often the opposite drop back, switch to every-other-day dosing, and let receptors stabilize before going up again

doi: 10.1016/S1262-3636(17)30070-8 196 DongZZhuangQYeXNingMWuSLuLet al