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SLC7A11 and SLC3A2 mediate ER inhibition of ferroptosis in ER+ breast cancer cells To investigate whether SLC7A11 and SLC3A2 are involved in ER-regulated ferroptosis, we examine the effects of knocking down SLC7A11 and SLC3A2 using two different shRNAs in ER+ breast cancer cells (Fig

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Quercetin reversed these alterations, restoring antioxidant enzyme activities, GSH levels, and Zn concentrations while reducing MDA levels and DNMT3a expression