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Irbesartan, an angiotensin receptor blocker, inhibits the activation of the Hippo/YAP1/TAZ signaling pathway, decreasing c-Jun expression, which upregulates iron metabolism genes and suppresses ferroptosis

Extracellular fluid viscosity enhances cell migration and cancer dissemination

This form of administration requires very large volumes of the solution, occasionally as much as 300 mL during a single treatment period

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cited to illustrate range of doses explored in mood disorders and that even lower doses had some effect

Although the NOX family member knockouts are remarkably normal, they are activated in pathological conditions, making them therapeutic targets