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Primary function: Reconstitution and dilution of powdered or concentrated drug products before parenteral (IV, IM, or SC) administration, not for direct IV infusion alone

The first and rate-limiting step involves generating the dipeptide -glutamylcysteine (-EC) from glutamate and cysteine, catalyzed by glutamate cysteine ligase (GCL)

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FIGURE 1 3.2 Targeted metabolomics reveals metabolic reprogramming in LPS- and papain-induced pneumonia Targeted metabolomics was performed on lung tissues, and 324 polar metabolites were detected (Supplementary Table S1)