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The cost does rise as doses increase, but I appreciate the transparency and inclusivity

10.1038/s41575-019-0158-2 54 LiC.XiaJ.DengJ.JiangJ

In particular, we focused on the p21 N-terminal cyclin-CDK binding domain, required for inhibition of G1/S cell cycle progression, and the C-terminal PCNA binding domain involved in suppressing DNA synthesis (Chen et al, 1995) (Fig 2D)

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Simple temperature indicators or more sophisticated temperature logging devices can help ensure that storage conditions remain within acceptable ranges