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doi: 10.1016/j.biocel.2006.07.001

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Emerging research suggests that hydrogen water may not only provide direct antioxidant effects but also enhance the body's endogenous antioxidant systems, including glutathione reductase activity

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In diabetic nephropathy, inhibition of HMGB1 has been observed to attenuate podocyte apoptosis and epithelial-mesenchymal transition [325]