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The efficacy of Kygevvi to treat patients with TK2d who start to show symptoms when they are 12 years old or younger was established based on data from one phase 2 clinical study, two retrospective chart review studies, and an expanded access program

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Self-reported titration described in community sources: 0.25 mg 3x/week for week 1, then 0.5 mg 3x/week thereafter, with optional 8-week-on / 8-week-off cycling