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Excess NADH (and concomitant NAD depletion) directly impairs this NAD-dependent step, causing a buildup of upstream glycolytic intermediates and a block in downstream flux 112,113

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"If people feel judged for the choices they're making about their health, that can influence what they're willing to do," she said

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This disconnect is not unique to BPC-157, but reflects a broader trend within the biohacking movement, where enthusiasm and anecdotal claims for emerging therapies can sometimes outpace the pace of clinical research and regulatory review