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22:705-707 [PubMed: 37944573] 364

How This Study Compares to Other Meta-Analyses Every meta-analysis conducted since 2022 has confirmed the same conclusion: microneedling, alone or in combination with topical treatment, produces significantly better outcomes than topical treatment alone

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This can lead to daytime fatigue, headaches and other short-term symptoms, as well as an increased risk of cardiovascular disease, diabetes and mental health changes