Cellular mechanisms of Decreased Response Desensitization Downregulation Tachyphylaxis Tolerance Desensitization Desensitization refers to a reduced response to an agonist drug due to over activation of a receptor (high doses, prolonged exposure to agonist)
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To maintain the intracellular redox balance, GSH is replenished through the reduction of GSSG by glutathione reductase enzyme
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However, results vary, and it's important to maintain realistic expectations and follow a skincare regimen recommended by a dermatologist