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These data were confirmed in a pooled analysis of the two trials with a reduction of CRP level with semaglutide of 43% vs 10% with placebo (OR 0.64, 95% C.I

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2 The effects of the DPP-4 inhibitors are glucose-dependent and so there is a low risk of hypoglycaemia

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Staying well hydrated is particularly important if vomiting or diarrhoea occurs, as persistent fluid loss can place strain on the kidneys

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