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SLC22A12 gene encoding for the urate transporter hURAT1 defects leads to primary renal hypouricemia characterized by increased UA excretion from a reduced reabsorption (Tana et al., 2018)

Persistently high TSH causes thyroid hypertrophy (goiter)

In murine models of melanoma and colorectal cancer, simvastatin stimulates antitumor immune responses on its own and improves responses to -PD1 immunotherapy, accompanied by an increase in intratumoral lipid peroxidation

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Serum Vitamin D(3) Concentration, Sleep, and Cognitive Impairment among Older Adults in China

Utilisation en cas d'insuffisance rnale svre Chez les patients souffrant d'insuffisance rnale svre, les doses peuvent ventuellement tre augmentes (ou l'intervalle d'administration raccourci) car la rponse thrapeutique la vitamine B12 est parfois plus faible chez ces patients