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Distilled water is basically tap water that went to a very fancy finishing school

Changes in the levels of both circulating biomarkers were correlated with the TMAO levels (rho = 0.568, p = 0.002

In contrast, immune signaling in the TG was largely resolved, while OXPHOS and mitophagy pathways were upregulated, indicating a regenerative mitochondrial response ( Figure 3B

Their use in certain longevity contexts may involve off-label applications

**Indirect Risks are Real:** Common GI side effects (nausea in up to 44%, diarrhea in up to 30%) can cause dehydration, making UV exposure and heat stress riskier