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Endocr Dev (2013) 24:11827

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314,315 The dual inhibition of KPT-9274 allows targeting of NAD + regeneration and PAK4 signaling, which are essential for tumor development and survival, making KPT-9274 an attractive drug candidate for use in chemotherapy

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125,126,127 Glutamine in cancer Tumor cells are urgent consumers of Gln

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