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Trulicity users in AWARD-11 lost approximately 710 lbs at the highest dose over 36 weeks

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Obesity is associated with low-grade systemic inflammation, characterized by increased levels of inflammatory markers such as Toll-like receptor 4 (TLR4), tumor necrosis factor-alpha (TNF-), IL-6, IL-1 [36], IL 17, leptin [37], and resistin [38]

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As reported previously [14, 15], glucose stimulated GLP-1 secretion, which increased approximately three-fold