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Sikiri P, Seiwerth S, Rucman R, et al

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A block in MMUT activity leads to accumulation of methylmalonic acid and other propionyl-CoA derived catabolites, which in turn have secondary effects on associated pathways and play a major role in the pathogenesis of MMA (3)

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Uniquely, studies suggest that Ipamorelin mimics the natural pulsatile secretion of GH without significantly stimulating the release of adrenocorticotropic hormone (ACTH), cortisol, or prolactin