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Similarly, in microglia mitochondria, levels of 8-hydroxy-2-deoxyguanosine (8-OHdG) have been shown to be regarded as a marker of DNA/ RNA oxidation due to the lack of protection of mitochondrial DNA (mtDNA) by histone proteins and its own limited repair capacity (41)
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This selectivity makes AOD 9604 a promising candidate for weight management, as it can target and mobilize fat stores without the growth-promoting effects associated with human growth hormones
Dai WL, et al
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