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By 6 months, the combination therapy achieved a 52% reduction in UACR, which was 29% greater than finerenone alone and 32% greater than empagliflozin alone, with most of the effect seen within 4 weeks

A separate comprehensive review published in May 2026 in Exploratory Research and Hypothesis in Medicine concluded that GLP-1 receptor agonists appear to favorably affect all 12 recognized hallmarks of aging in laboratory and early clinical settings

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Its efficacy and safety are well documented

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