This is normal and expected, not a sign that you are taking "too much." The tirzepatide dosage chart in units provides injectable reference points for comparison
The letter also detailed prior communications sent by the FDA to the manufacturer about their marketing efforts
Insulin resistance : Reduced cellular response to insulin, leading to high blood sugar
doi: 10.1016/j.bbagen.2013.04.016

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For the best results we recommend weekly infusions for 3 months, then monthly for maintenance.