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TMAO-induced vascular dysfunction TMAO increases the expression of macrophage scavenger receptor cluster of differentiation 36 (CD36) and scavenger receptor class A type 1 (SR-A1), which causes foam cell production [104, 105]
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Glucose control and the effect of empagliflozin on kidney outcomes in type 2 diabetes: an analysis from the EMPA-REG OUTCOME trial
While skeletal muscle detoxifies ammonia, hyperammonemia decreases serum BCAA and increases myostatin levels, both of which result in inhibition of mammalian target of rapamycin signaling and decreased protein synthesis [41, 42]
It uses the Na + -driven LC / organic cation transporter-2 (OCTN-2) for its transport into the oocytes [74]
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