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Special caution is advised for individuals who have altered vitamin B12 absorption due to certain medical conditions or medications, or who are individually sensitive to higher doses

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B12 is found in animal foods such as meat, poultry and seafood, while plant foods are an excellent source of the other B vitamins

Accordingly, deletion of Gclc in B cells leads to a specific loss of MZB content but not FoB

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The decision to use either medication can depend on a patient's overall health profile and the presence of comorbid conditions