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There is a theoretical concern, supported by some biological evidence, that elevated IGF-1 activity in a patient with occult or a history of certain hormone-sensitive cancers could be problematic

Concurrently, the rs664589 G allele of MALAT1 has been associated with a 1.33-fold increased risk of hypertension, particularly among individuals with obesity, male sex, or a history of smoking and alcohol use

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Injection-site erythema and localized warmth are more pronounced at higher volumes

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