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Indeed, in our first on-treatment analysis at week 208, weight loss was greater (11.7% for semaglutide) compared with the in-trial analysis (10.2% for semaglutide)

2020 Aug 4;32(2):154-175

The meta-analysis of the randomized trials of folate supplementation also supports this conclusion

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People with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) or with a personal or family history of medullary thyroid carcinoma (MTC) should not use semaglutide

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