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Ca 2+ is not metabolized and an overload of mitochondrial Ca 2+ may break down the electrochemical proton gradient resulting in a deficit of ATP followed by necrosis [89]

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At this point, we were sure that the crosstalk between androgen and Wnt/-catenin signaling was involved in this process

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This decline correlates with many common aging complaints including decreased energy, increased body fat, reduced muscle mass, thinner skin, and impaired cognitive function