STEP-1 (NEJM 2021) established the weight-loss efficacy of semaglutide 2.4mg: 1,961 adults with obesity, mean 14.9% weight loss at 68 weeks versus 2.4% on placebo
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Most recently, researchers in Pomona, California, found significant improvements in cognitive function in a mouse model of Angelman Syndrome, a genetic disorder which, amongst other abnormalities, presents as severe deficits in both motor and cognitive functions
