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This intricate crosstalk highlights the interconnectedness of the gut-brain axis, where disruptions in microbial balance (dysbiosis) or microglial dysfunction can contribute to neurodegenerative and neuroinflammatory disorders Figure 1
Several activities that we perform on a daily basis can deplete glutathione
It may also improve the quality and endurance of the muscles
Importantly, the positive correlation observed between VPAs inhibitory effect on ferroptosis and its antiepileptic effect strongly indicates that modulation of ferroptosis might be an important avenue for harnessing the therapeutic potential of antiepileptic drugs (85)
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