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Instead, supplements should be viewed as part of a balanced approach that includes nutritious eating, regular physical activity, quality sleep, and other healthy lifestyle habits

In practice, this means letting each dose settle for two to four weeks before stepping up

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Interestingly, the phospholipid metabolism is also possibly altered by riboflavin deficiency, because PLCA, an enzyme catalyzing the acylation of lysophosphatidic acid to form phosphatidic acid 35 , was up-regulated at the protein expression level in this study