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A computationally designed antigen eliciting broad humoral responses against SARS-CoV-2 and related sarbecoviruses

This condition affects millions of people, particularly those of East Asian descent

Funding This work was supported by grants from the Natural Science Foundation of Guangdong Province (2018A030313846 and 2021A1515012593), the Science and Technology Planning Project of Guangdong Province (2019A030317020), the National Natural Science Foundation of China (81802257, 81871859, 81772457, 82172750, 82172811, and 82260546), the Guangdong Basic and Applied Basic Research Foundation (GuangdongGuangzhou Joint Funds) (2022A1515111212), and the Science and Technology Program of Guangzhou (2023A04J1257)

A recent survey from the North American Neuro-Ophthalmology Society (NANOS) recently demonstrated that the median wait time to receive care for new patients, many of whom present with acute concern, is 6 weeks [1]

consequently, the latter induces negative feedback on the HPG axis, leading to sub-fecundity and infertility

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