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Most patients starting with normal b12 levels and no significant risk factors do not require supplementation

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Potential Side Effects and Safety Considerations General Tolerance GHK-Cu is considered safe and non-toxic , with a safety profile similar to placebo in clinical trials (Abdulghani et al., 1999)

Animal doses cannot be directly extrapolated to humans Key Research Findings# Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice , published in Biochemical Pharmacology (Neelakantan H et al., 2018

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