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Once ipamorelin binds to GHSR-1a, it activates G-protein-coupled receptor signaling that triggers calcium influx and cyclic signaling pathways associated with GH vesicle exocytosis

dose adjustments of concomitant medications may be necessary Renal function : Dehydration from gastrointestinal side effects may precipitate acute kidney injury, particularly in patients with pre-existing renal impairment