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and SH2 (664-768) (Figure 4C), and then identified an interaction between the CCD domain of STAT3 and GSTP1 by means of a GST pull-down assay (Figure 4C)

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Treatment depends on the cause and severity: oral supplementation suffices for dietary deficiency, whilst patients with pernicious anaemia or malabsorption typically require intramuscular hydroxocobalamin injections

For healthy individuals in a research setting using appropriate doses, this temporary increase is a normal physiological response (reflex tachycardia) to vasodilation

In these individuals, methylfolate or folinic acid may represent a more appropriate choice