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Hashimoto, N

To evaluate the incidence of MACE-4 events in patients treated with tirzepatide compared to the control group, a meta-analysis was conducted using data from 7778 patients enrolled in the SURPASS-4 study, SURPASS Clinical Trails Program (which includes 7 randomized clinical trials), and SURMOUNT-1

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Neuroendocrine experiments use pituitary cell cultures (GH3, AtT-20) and primary pituitary tissue explants to measure peptide release in response to DSIP

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Conversely, there was a possible reduction in activation within the secondary somatosensory cortex, an area involved in processing sensory information, specifically when under the influence of visual stimuli, differing from responses observed with the placebo