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Eligibility for Tirzepatide treatment includes a body mass index (BMI) of 30 or higher (obese), or those who possess a BMI of 27 or above (overweight) along with the presence of at least one weight-related health issue

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Protein abundances of HDAC proteins in the CPTAC AML cohort (n = 162 patients) are shown as a boxplot

These results corroborate findings from placebo-controlled studies, which showed that both drugs are highly effective, but Zepbound is superior

For this variable, ex vivo LPS-stimulated cells showed a lower OCR, compared to the others

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