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4.3 Integrated multi-omics insights into DKD regulation Beyond transcriptomic analysis, the integration of single-cell RNA sequencing with assay for transposase-accessible chromatin (scATAC-seq) has enabled deeper insight into how gene regulatory networks are remodeled under diabetic conditions (Figure 3)

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As a result, lower drug administration requirements are feasible [17], so no modification of the therapeutic agent nor coupling the drug to any carrier is required [11]

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