7 Semaglutides role in the medical triad of diabetes, obesity, and cancer The prevalence of T2DM has increased significantly in the past decades
With the guts biome important to GLP-1 secretion, fresh, fermented and high fibre foods are important to its health but can come with side effects, DAmbrosio says
Measuring body composition (fat versus lean mass) should become routine in the management of patients on GLP-1 medications. The Takeaway While GLP-1 medications are effective for weight loss, rapid weight reduction can lead to significant loss of fat-free mass, including muscle
Despite widespread claims on social media and unregulated websites, no GLP-1 patches are currently approved or available for clinical use in the UK
"This has been shown in studies, often [with] fewer side effects." More oral GLP-1s may be coming in 2026, according to Decotiis, including an Orforglipron application by Lilly and a new combination Novo Nordisk drug, which is pending approval later next year
Others might want to try it to reduce how much alcohol they drink. There are also a growing number of people interested in microdosing GLP-1s for longevity