The second trial, IMPACT 2, had a similar design, except that crossover to active therapy for the placebo arm took place at 24 weeks, although patients with active disease could enter an early escape at 16 weeks
Therefore, further discussions and studies will be needed to understand the action of acetaminophen
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10.1182/blood.v76.5.930.930 Blood 31 ChenL.YangG
Long-term use may increase sun sensitivity, so sunscreen is important
Ensure the container is stood upright and tightly closed after use to protect the formulation from contamination