Peptide-based targeted therapeutics and apoptosis imaging probes for cancer therapy
Acknowledgements This work was supported by the National Natural Science Foundation of China (82073313 to D.L.), the joint project of the State Administration of Traditional Chinese Medicine and Health Commission of Shandong Province (GZY-KJS-SD-2023-094), the Traditional Chinese Medicine Special Project of Binzhou Medical University Affiliated Traditional Chinese Medicine Hospital (2023ZYZX02) and the 2023 Qilu Biancang Traditional Chinese Medicine Talent Cultivation Project (to D.L.)
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TBK1 then phosphorylates and activates both the IRF3 pathway and the NF-B pathway, triggering the transcription of proinflammatory cytokines, antiviral chemokines, interferon-stimulated genes (ISGs), and type I IFNs