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Consequently, maintaining ROS homeostasis is critical for the prevention and treatment of these diseases

J Pharm Investig 48:431441 Kim J, Choi J, Kang H, Ahn J, Hutchings J, Van Niekerk C, Park D, Kim J, Jeon Y, Nam K, Shin S, Shin BS (2022) Safety, tolerability, and pharmacokinetics of Telacebec (Q203), a new antituberculosis agent, in healthy subjects

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Emerging evidence reveals that intracellular lactate modulates PASMC function by inhibiting SENP1, stabilizing APC4 SUMOylation, and promoting UBE2C-APC/C interaction, a key complex for degrading mitotic cyclins

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