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The most recent systematic review, published last year in an orthopaedic journal, screened 544 papers and found one human study that qualified: a retrospective look at 12 people who had the peptide injected into an arthritic knee, seven of whom reported relief lasting more than six months

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Even so, it can irritate the skin when used with tretinoin

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Potential Side Effects & Safety Considerations You've probably wondered if the serum's tiny drops could ever cause more trouble than they solve