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a , Structures of agonist-bound GLP-1R

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So-called Ozempic face, or a loss of fat in the face that can lead to a gaunt appearance, sagging skin and more obvious wrinkles, is not officially listed as a side effect of the medication, but some users have reported looking older after taking Ozempic for a while

The researchers included only studies that reported a mean weight loss of 3 kg with GLP-1RA treatment, to ensure that significant post-cessation weight regain could be captured

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